Tirzepatide in Sun City AZ: A Breakthrough Treatment for Weight Loss
Tirzepatide is an innovative weight loss treatment that combines the benefits of GLP-1 and GIP receptor agonism, helping to control hunger and regulate blood sugar. This breakthrough medication has demonstrated impressive effectiveness in reducing body weight in clinical studies. Dr. Manish Sahni, MD, provides professional guidance in using Tirzepatide, creating personalized weight loss plans to support long-term health goals. For more information, contact us or request an appointment online. We are located at 13000 N. 103rd Avenue Suite 60, Sun City, AZ 85351.


Table of Contents:
Who is a good candidate for tirzepatide therapy for weight loss and what criteria determine eligibility?
How does tirzepatide support weight loss, and what results can patients typically expect over time?
What are the potential risks or side effects of tirzepatide, and how are they monitored?
Are lifestyle changes — such as diet and exercise — required in conjunction with tirzepatide for optimal results?
Why Choose Dr. Manish Sahni, MD for Tirzepatide-Based Weight Loss at Centra Internal Medicine
Tirzepatide is a medication that was originally developed for type 2 diabetes but is now also being prescribed for weight management in adults with obesity or overweight conditions.
Our team carefully evaluates patients to determine eligibility for tirzepatide therapy. Good candidates include adults with:
• A body mass index (BMI) of 30 kg/m² or higher (classified as obesity), or
• A BMI of 27 kg/m² or higher (overweight) who also have at least one weight-related health condition, such as:
• Hypertension (high blood pressure)
• Type 2 diabetes
• Dyslipidemia (abnormal cholesterol)
• Obstructive sleep apnea
Comprehensive Evaluation Process
Before starting tirzepatide, our providers will conduct a thorough assessment of your overall health, medical history, and current medications. This helps us ensure the safe use of tirzepatide by screening for contraindications or potential drug interactions.
Tirzepatide is not recommended for individuals with:
• A personal or family history of medullary thyroid carcinoma
• Multiple endocrine neoplasia syndrome type 2
•A history of severe gastrointestinal disease, pancreatitis, or those who are pregnant or planning pregnancy
Tirzepatide is unique because it acts as a dual agonist for two important gut hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By activating the receptors for both GLP-1 and GIP, tirzepatide helps your body in several ways:
• Enhances insulin secretion in response to meals
• Reduces glucose production by the liver
• Slows stomach emptying, leading to increased feelings of fullness
These combined effects help regulate blood sugar and curb appetite, making it easier for patients to reduce food intake and achieve sustainable weight loss.
Clinical Benefits
Clinical studies have demonstrated that patients using tirzepatide for weight management can experience significant reductions in body weight. On average, patients may lose between 15% and 20% of their starting weight over 72 weeks when tirzepatide is used in combination with healthy lifestyle changes, such as improved diet and increased physical activity. Some individuals may achieve even greater results. Typically, weight loss begins within the first few weeks and continues throughout treatment.
Tirzepatide is a newer medication that has shown promising results in both blood sugar control and weight management. As with any medication, it is important that our patients understand the potential risks and side effects, and how we work together to monitor and manage them.
Common Side Effects and What to Expect
The most frequent side effects of tirzepatide involve the gastrointestinal system. Our patients may experience symptoms such as nausea, vomiting, diarrhea, decreased appetite, or constipation, especially in the first weeks of therapy. At Centra Internal Medicine, we help you manage these symptoms, and most patients find that they improve as the body adjusts to the medication. If side effects are bothersome or persistent, we encourage you to contact us so we can make any necessary adjustments to your care plan.
Other Potential Risks
Tirzepatide can, in some cases, cause low blood sugar (hypoglycemia). Our team will work closely with you to monitor your blood sugar levels and adjust your medications as needed to minimize your risk. Be aware of symptoms such as shakiness, sweating, confusion, or severe dizziness, and notify us if they occur.
Another rare but serious risk is pancreatitis, which presents as severe abdominal pain, sometimes radiating to the back, and may be accompanied by nausea and vomiting. If you experience these symptoms, please contact usimmediately or seek emergency care.
Safety Precautions
There have also been concerns about the risk of thyroid tumors, including medullary thyroid carcinoma, based on animal studies. For this reason, tirzepatide is not recommended for patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2. Before starting tirzepatide, your provider will thoroughly review your medical and family history to ensure this medication is appropriate for you.
While allergic reactions to tirzepatide are rare, they can occur. Symptoms such as rash, itching, swelling, or difficulty breathing should be reported to us immediately.
Ongoing Monitoring at Centra Internal Medicine
To ensure your safety and the effectiveness of your treatment, our providers schedule regular follow-up appointments. During these visits, we assess how you’re feeling and monitor your blood sugar. We also watch for any signs of thyroid issues and encourage you to report any new neck masses or trouble swallowing.
Tirzepatide, a medication shown to be highly effective for both blood sugar control and weight loss in individuals with diabetes, obesity, or who are overweight.
Our experience at Centra Internal Medicine aligns with the latest clinical research and expert guidelines. Our providers work closely with you to develop sustainable adjustments to your diet and exercise routines, maximizing the benefits of tirzepatide.
Nutrition plays a key role in enhancing the effects of tirzepatide. We encourage our patients to follow a balanced diet rich in vegetables, fruits, lean proteins, whole grains, and healthy fats. Our medical team can help you reduce your intake of processed foods, refined sugars, and saturated fats, supporting better blood sugar control and greater weight loss.
Physical activity is also essential. We help you find exercise routines that fit your abilities and preferences—whether it’s brisk walking, swimming, cycling, or resistance training. Regular exercise not only aids in weight management but also improves your body’s response to insulin and lowers the risk of complications from diabetes and obesity.
It’s important to remember that lifestyle changes are not optional when using medications like tirzepatide; they are an integral part of achieving optimal results. By combining tirzepatide with dietary improvements and regular activity, you can enhance your health, reduce cardiovascular risks, and achieve lasting well-being.
Centra Internal Medicine stands at the forefront of advanced obesity management, offering patients innovative, evidence-based treatment options such as tirzepatide. Under the expert care of Dr. Manish Sahni, MD—a board-certified internist with a proven track record in managing complex metabolic conditions including obesity and type 2 diabetes—patients receive individualized care tailored to their unique health needs and goals.
At Centra Internal Medicine, our team is dedicated to providing comprehensive weight management solutions. We utilize Tirzepatide, a next-generation GLP-1/GIP receptor agonist, which has demonstrated substantial benefits in clinical trials for both weight loss and glycemic control. Each patient undergoes a thorough medical assessment, including metabolic evaluations and a review of individual health history, ensuring the safest and most effective approach to weight loss.
Our practice emphasizes patient education and collaborative decision-making. Dr. Sahni personally guides patients through the process, explaining how tirzepatide works, what to expect during treatment, and how to make sustainable lifestyle changes. Dr. Sahni closely monitors for potential side effects and adjusts therapy as needed, ensuring optimal outcomes throughout your weight loss journey. Our holistic, compassionate care model makes Centra Internal Medicine a trusted destination for effective, medically supervised weight management.
By choosing Centra Internal Medicine, you gain access to state-of-the-art therapies, a dedicated medical team, and ongoing support for achieving and maintaining a healthier weight—for life. For more information, contact us or request an appointment online. We are located at 13000 N. 103rd Avenue Suite 60, Sun City, AZ 85351. We serve patients from Sun City AZ, Youngtown AZ, El Mirage AZ, Peoria AZ, Bumstead AZ, and surrounding areas.
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▸ Joint Injections
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▸ Migraines
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▸ Tirzepatide
▸ Phentermine
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▸ FDA-Approved Oral Semaglutide (GLP-1)

Additional Services You May Need
▸ Aesthetics
▸ Allergies
▸ Annual Physical Exams
▸ Gynecological Exams
▸ High Blood Pressure
▸ Immunizations
▸ Joint Injections
▸ Lab Services
▸ Migraines
▸ Minor Surgical Procedures
▸ Pre-op Clearance Exams
▸ Double Chin
▸ Acute Disease Management
▸ Mole Removal
▸ Primary Care
▸ Same Day Appointments
▸ Sculpsure
▸ Sick Visits
▸ Wound Care
▸ TempSure
▸ Testosterone Replacement Therapy
▸ Video Visits
▸ Weight Management
▸ Wellness
▸ Women’s Health
▸ Chronic Disease Management
▸ CDL Physical Exam
▸ Auto Accident Injury
▸ Tirzepatide
▸ Semaglutide
▸ Phentermine
▸ Contrave
▸ Nutritional Coaching
▸ DOT Physicals
▸ Vaccinations
▸ FDA-Approved Oral Semaglutide (GLP-1)


